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Anti-ganglioside antibodies induced in chickens by an alum-adsorbed anti-idiotype antibody targeting NeuGcGM3

Racotumomab is a murine anti-idiotype cancer vaccine targeting NeuGcGM3 on melanoma, breast, and lung cancer. In order to characterize the immunogenicity of alum-adsorbed racotumomab in a non-clinical setting, Leghorn chickens were immunized in dose levels ranging from 25 μg to 1600 μg. Racotumomab...

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Detalhes bibliográficos
Main Authors: Guthmann, Marcelo D., Venier, Cecilia, Toledo, Darien, Segatori, Valeria I., Alonso, Daniel F., Fainboim, Leonardo, Vázquez, Ana M., Ostrowski, Hector
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547288/
https://ncbi.nlm.nih.gov/pubmed/23335925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00422
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