Anti-ganglioside antibodies induced in chickens by an alum-adsorbed anti-idiotype antibody targeting NeuGcGM3.

Racotumomab is a murine anti-idiotype cancer vaccine targeting NeuGcGM3 on melanoma, breast and lung cancer. In order to characterize the immunogenicity of alum-adsorbed racotumomab in a non-clinical setting, Leghorn chickens were immunized in dose levels ranging from 25 µg to 1600 &#18...

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Detalhes bibliográficos
Main Authors: Marcelo David Guthmann, Cecilia eVenier, Darien eToledo, Valeria I Segatori, Daniel F Alonso, Leonardo eFainboim, Ana María eVázquez, Hector eOstrowski
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013-01-01
Colecção:Frontiers in Immunology
Assuntos:
antibody responses
Tumor antigens
Racotumomab
anti-idiotype antibody
NeuGcGM3
Leghorn chickens
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00422/full
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