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Human Apolipoprotein E Isoforms differentially affect Bone Mass and Turnover in vivo

The primary role of apolipoprotein E (apoE) is to mediate the cellular uptake of lipoproteins. However, a new role for apoE as a regulator of bone metabolism in mice has recently been established. In contrast to mice, the human APOE gene is characterized by three common isoforms APOE ε2, ε3 and ε4 t...

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Autors principals: Dieckmann, Marco, Beil, F. Timo, Mueller, Brigitte, Bartelt, Alexander, Marshall, Robert P., Koehne, Till, Amling, Michael, Ruether, Wolfgang, Cooper, Jackie A., Humphries, Steve E., Herz, Joachim, Niemeier, Andreas
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547162/
https://ncbi.nlm.nih.gov/pubmed/22991192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1757
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