Impaired tumor antigen processing by immunoproteasome-expressing CD40-activated B cells and dendritic cells

Professional APCs, such as dendritic cells, are routinely used in vitro for the generation of cytotoxic T lymphocytes specific for tumor antigens. In addition to dendritic cells, CD40-activated B cells and variant K562 leukemic cells can be readily transfected with nucleic acids for in vitro and in...

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Autori principali: Anderson, Karen S., Zeng, Wanyong, Sasada, Tetsuro, Choi, Jaewon, Riemer, Angelika B., Su, Mei, Drakoulakos, Donna, Kang, Yoon-Joong, Brusic, Vladimir, Wu, Catherine, Reinherz, Ellis L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547125/
https://ncbi.nlm.nih.gov/pubmed/21400024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-0995-5
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