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Tissue Factor Signals Airway Epithelial Basal Cell Survival via Coagulation and Protease-Activated Receptor Isoforms 1 and 2

Tissue factor (TF) initiates the extrinsic coagulation cascade and is a high-affinity receptor for coagulation factor VII. TF also participates in protease-activated receptor (PAR)1 and PAR2 activation. Human epithelial basal cells were previously purified on the basis of TF expression. The purpose...

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Autors principals: Ahmad, Shama, Ahmad, Aftab, Rancourt, Raymond C., Neeves, Keith B., Loader, Joan E., Hendry-Hofer, Tara, Di Paola, Jorge, Reynolds, Susan D., White, Carl W.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547080/
https://ncbi.nlm.nih.gov/pubmed/23065128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0189OC
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