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Erythrocytes Induce Proinflammatory Endothelial Activation in Hypoxia

Although exposure to ambient hypoxia is known to cause proinflammatory vascular responses, the mechanisms initiating these responses are not understood. We tested the hypothesis that in systemic hypoxia, erythrocyte-derived H(2)O(2) induces proinflammatory gene transcription in vascular endothelium....

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Detalhes bibliográficos
Main Authors: Huertas, Alice, Das, Shonit R., Emin, Memet, Sun, Li, Rifkind, Joseph M., Bhattacharya, Jahar, Bhattacharya, Sunita
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547079/
https://ncbi.nlm.nih.gov/pubmed/23043086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2011-0402OC
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