PIP5KIβ Selectively Modulates Apical Endocytosis in Polarized Renal Epithelial Cells

Localized synthesis of phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P(2)] at clathrin coated pits (CCPs) is crucial for the recruitment of adaptors and other components of the internalization machinery, as well as for regulating actin dynamics during endocytosis. PtdIns(4,5)P(2) is synthesized...

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Detalhes bibliográficos
Main Authors: Szalinski, Christina M., Guerriero, Christopher J., Ruiz, Wily G., Docter, Brianne E., Rbaibi, Youssef, Pastor-Soler, Núria M., Apodaca, Gerard, Puthenveedu, Manojkumar A., Weisz, Ora A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547069/
https://ncbi.nlm.nih.gov/pubmed/23342003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053790
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