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Shear stress-dependent regulation of apical endocytosis in renal proximal tubule cells mediated by primary cilia

The kidney has an extraordinary ability to maintain stable fractional solute and fluid reabsorption over a wide range of glomerular filtration rates (GFRs). Internalization of filtered low molecular weight proteins, vitamins, hormones, and other small molecules is mediated by the proximal tubule (PT...

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Autors principals: Raghavan, Venkatesan, Rbaibi, Youssef, Pastor-Soler, Núria M., Carattino, Marcelo D., Weisz, Ora A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060694/
https://ncbi.nlm.nih.gov/pubmed/24912170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402195111
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