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Expansion on Stromal Cells Preserves the Undifferentiated State of Human Hematopoietic Stem Cells Despite Compromised Reconstitution Ability

Lack of HLA-matched hematopoietic stem cells (HSC) limits the number of patients with life-threatening blood disorders that can be treated by HSC transplantation. So far, insufficient understanding of the regulatory mechanisms governing human HSC has precluded the development of effective protocols...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Magnusson, Mattias, Sierra, Maria I., Sasidharan, Rajkumar, Prashad, Sacha L., Romero, Melissa, Saarikoski, Pamela, Van Handel, Ben, Huang, Andy, Li, Xinmin, Mikkola, Hanna K. A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547050/
https://ncbi.nlm.nih.gov/pubmed/23342037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053912
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