Interleukin-1β Regulates Fat-Liver Crosstalk in Obesity by Auto-Paracrine Modulation of Adipose Tissue Inflammation and Expandability

The inflammasome has been recently implicated in obesity-associated dys-metabolism. However, of its products, the specific role of IL-1β was clinically demonstrated to mediate only the pancreatic beta-cell demise, and in mice mainly the intra-hepatic manifestations of obesity. Yet, it remains largel...

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Bibliographic Details
Main Authors: Nov, Ori, Shapiro, Hagit, Ovadia, Hilla, Tarnovscki, Tanya, Dvir, Irit, Shemesh, Elad, Kovsan, Julia, Shelef, Ilan, Carmi, Yaron, Voronov, Elena, Apte, Ron N., Lewis, Eli, Haim, Yulia, Konrad, Daniel, Bashan, Nava, Rudich, Assaf
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547030/
https://ncbi.nlm.nih.gov/pubmed/23341960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053626
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