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Base Excision Repair in Physiology and Pathology of the Central Nervous System

Relatively low levels of antioxidant enzymes and high oxygen metabolism result in formation of numerous oxidized DNA lesions in the tissues of the central nervous system. Accumulation of damage in the DNA, due to continuous genotoxic stress, has been linked to both aging and the development of vario...

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Autors principals: Bosshard, Matthias, Markkanen, Enni, van Loon, Barbara
Format: Artigo
Idioma:Inglês
Publicat: Molecular Diversity Preservation International (MDPI) 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546685/
https://ncbi.nlm.nih.gov/pubmed/23203191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131216172
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