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Base Excision Repair in Physiology and Pathology of the Central Nervous System

Relatively low levels of antioxidant enzymes and high oxygen metabolism result in formation of numerous oxidized DNA lesions in the tissues of the central nervous system. Accumulation of damage in the DNA, due to continuous genotoxic stress, has been linked to both aging and the development of vario...

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Detalhes bibliográficos
Main Authors: Bosshard, Matthias, Markkanen, Enni, van Loon, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546685/
https://ncbi.nlm.nih.gov/pubmed/23203191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131216172
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