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Optimization of the Bacterial Cytochrome P450 BM3 System for the Production of Human Drug Metabolites
Drug metabolism in human liver is a process involving many different enzymes. Among them, a number of cytochromes P450 isoforms catalyze the oxidation of most of the drugs commercially available. Each P450 isoform acts on more than one drug, and one drug may be oxidized by more than one enzyme. As a...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Molecular Diversity Preservation International (MDPI)
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3546669/ https://ncbi.nlm.nih.gov/pubmed/23443101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131215901 |
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