The Transcription Factor ZNF217 Is a Prognostic Biomarker and Therapeutic Target during Breast Cancer Progression

The transcription factor ZNF217 is a candidate oncogene in the amplicon on chromosome 20q13 that occurs in 20% to 30% of primary human breast cancers and that correlates with poor prognosis. We show that Znf217 overexpression drives aberrant differentiation and signaling events, promotes increased s...

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Huvudupphovsmän: Littlepage, Laurie E., Adler, Adam S., Kouros-Mehr, Hosein, Huang, Guiqing, Chou, Jonathan, Krig, Sheryl R., Griffith, Obi L., Korkola, James E., Qu, Kun, Lawson, Devon A., Xue, Qing, Sternlicht, Mark D., Dijkgraaf, Gerrit J. P., Yaswen, Paul, Rugo, Hope S., Sweeney, Colleen A., Collins, Colin C., Gray, Joe W., Chang, Howard Y., Werb, Zena
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546490/
https://ncbi.nlm.nih.gov/pubmed/22728437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0093
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