Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with ERalpha

BACKGROUND: The ZNF217 gene, encoding a C(2)H(2) zinc finger protein, is located at 20q13 and found amplified and overexpressed in greater than 20% of breast tumors. Current studies indicate ZNF217 drives tumorigenesis, yet the regulatory mechanisms of ZNF217 are largely unknown. Because ZNF217 asso...

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Autori principali: Frietze, Seth, O’Geen, Henriette, Littlepage, Laurie E, Simion, Catalina, Sweeney, Colleen A, Farnham, Peggy J, Krig, Sheryl R
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082627/
https://ncbi.nlm.nih.gov/pubmed/24962896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-520
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