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An analysis and validation pipeline for large-scale RNAi-based screens
Large-scale RNAi-based screens are a major technology, but require adequate prioritization and validation of candidate genes from the primary screen. In this work, we performed a large-scale pooled shRNA screen in mouse embryonic stem cells (ESCs) to discover genes associated with oxidative stress r...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3546318/ https://ncbi.nlm.nih.gov/pubmed/23326633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01076 |
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