The effects of thiazolidinediones (TZD) on human bone marrow stromal cell differentiation in vitro and in TZD-treated patients with type 2 diabetes

Thiazolidinedione (TZD) therapy has been associated with increased risk of bone fractures. Studies in rodents have led to a model in which decreased bone quality in response to TZDs is due to a competition of lineage commitment between osteoblasts and adipocytes for a common precursor cell resulting...

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Hauptverfasser: Beck, George R., Khazai, Natasha B., Bouloux, Gary F., Camalier, Corinne E., Lin, Yiming, Garneys, Laura M., Siqueira, Joselita, Peng, Limin, Pasquel, Francisco, Umpierrez, Denise, Smiley, Dawn, Umpierrez, Guillermo E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546231/
https://ncbi.nlm.nih.gov/pubmed/23022285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2012.08.006
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