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A Sequence in Subdomain 2 of DBL1α of Plasmodium falciparum Erythrocyte Membrane Protein 1 Induces Strain Transcending Antibodies

Immunity to severe malaria is the first level of immunity acquired to Plasmodium falciparum. Antibodies to the variant antigen PfEMP1 (P. falciparum erythrocyte membrane protein 1) present at the surface of the parasitized red blood cell (pRBC) confer protection by blocking microvascular sequestrati...

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Main Authors: Blomqvist, Karin, Albrecht, Letusa, Quintana, Maria del Pilar, Angeletti, Davide, Joannin, Nicolas, Chêne, Arnaud, Moll, Kirsten, Wahlgren, Mats
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546040/
https://ncbi.nlm.nih.gov/pubmed/23335956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052679
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