Whole genome sequencing of phage resistant Bacillus anthracis mutants reveals an essential role for cell surface anchoring protein CsaB in phage AP50c adsorption

BACKGROUND: Spontaneous Bacillus anthracis mutants resistant to infection by phage AP50c (AP50(R)) exhibit a mucoid colony phenotype and secrete an extracellular matrix. METHODS: Here we utilized a Roche/454-based whole genome sequencing approach to identify mutations that are candidates for conferr...

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Hlavní autoři: Bishop-Lilly, Kimberly A, Plaut, Roger D, Chen, Peter E, Akmal, Arya, Willner, Kristin M, Butani, Amy, Dorsey, Shakia, Mokashi, Vishwesh, Mateczun, Alfred J, Chapman, Carol, George, Matroner, Luu, Truong, Read, Timothy D, Calendar, Richard, Stibitz, Scott, Sozhamannan, Shanmuga
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545897/
https://ncbi.nlm.nih.gov/pubmed/23098174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-246
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