Whole genome sequencing of phage resistant Bacillus anthracis mutants reveals an essential role for cell surface anchoring protein CsaB in phage AP50c adsorption

BACKGROUND: Spontaneous Bacillus anthracis mutants resistant to infection by phage AP50c (AP50(R)) exhibit a mucoid colony phenotype and secrete an extracellular matrix. METHODS: Here we utilized a Roche/454-based whole genome sequencing approach to identify mutations that are candidates for conferr...

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Detalhes bibliográficos
Main Authors: Bishop-Lilly, Kimberly A, Plaut, Roger D, Chen, Peter E, Akmal, Arya, Willner, Kristin M, Butani, Amy, Dorsey, Shakia, Mokashi, Vishwesh, Mateczun, Alfred J, Chapman, Carol, George, Matroner, Luu, Truong, Read, Timothy D, Calendar, Richard, Stibitz, Scott, Sozhamannan, Shanmuga
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545897/
https://ncbi.nlm.nih.gov/pubmed/23098174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-246
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