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Neddylation pathway regulates T-cell function by targeting an adaptor protein Shc and a protein kinase Erk signaling
NEDD8 (neural precursor cell expressed, developmentally down-regulated 8) is a ubiquitin-like molecule whose action on modifying protein substrates is critical in various cellular functions but whose importance in the immune system is not well understood. Here we investigated the role of protein ned...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545825/ https://ncbi.nlm.nih.gov/pubmed/23267066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213819110 |
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