Tumor cell-derived placental growth factor sensitizes antiangiogenic and antitumor effects of anti-VEGF drugs

The role of placental growth factor (PlGF) in modulation of tumor angiogenesis and tumor growth remains an enigma. Furthermore, anti-PlGF therapy in tumor angiogenesis and tumor growth remains controversial in preclinical tumor models. Here we show that in both human and mouse tumors, PlGF induced t...

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Bibliografiske detaljer
Main Authors: Hedlund, Eva-Maria Eleonora, Yang, Xiaojuan, Zhang, Yin, Yang, Yunlong, Shibuya, Masabumi, Zhong, Weide, Sun, Baocun, Liu, Yizhi, Hosaka, Kayoko, Cao, Yihai
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2013
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545771/
https://ncbi.nlm.nih.gov/pubmed/23267058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209310110
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