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Botulinum neurotoxin is shielded by NTNHA in an interlocked complex

Botulinum neurotoxins (BoNTs) are highly poisonous substances that are also effective medicines. Accidental BoNT poisoning often occurs through ingestion of Clostridium botulinum-contaminated food. Here, we present the crystal structure of a BoNT in complex with a clostridial non-toxic non-hemagglut...

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Bibliografiska uppgifter
Huvudupphovsmän: Gu, Shenyan, Rumpel, Sophie, Zhou, Jie, Strotmeier, Jasmin, Bigalke, Hans, Perry, Kay, Shoemaker, Charles B., Rummel, Andreas, Jin, Rongsheng
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545708/
https://ncbi.nlm.nih.gov/pubmed/22363010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1214270
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