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Botulinum neurotoxin is shielded by NTNHA in an interlocked complex

Botulinum neurotoxins (BoNTs) are highly poisonous substances that are also effective medicines. Accidental BoNT poisoning often occurs through ingestion of Clostridium botulinum-contaminated food. Here, we present the crystal structure of a BoNT in complex with a clostridial non-toxic non-hemagglut...

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Détails bibliographiques
Auteurs principaux: Gu, Shenyan, Rumpel, Sophie, Zhou, Jie, Strotmeier, Jasmin, Bigalke, Hans, Perry, Kay, Shoemaker, Charles B., Rummel, Andreas, Jin, Rongsheng
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545708/
https://ncbi.nlm.nih.gov/pubmed/22363010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1214270
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