Botulinum neurotoxin is shielded by NTNHA in an interlocked complex

Botulinum neurotoxins (BoNTs) are highly poisonous substances that are also effective medicines. Accidental BoNT poisoning often occurs through ingestion of Clostridium botulinum-contaminated food. Here, we present the crystal structure of a BoNT in complex with a clostridial non-toxic non-hemagglut...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gu, Shenyan, Rumpel, Sophie, Zhou, Jie, Strotmeier, Jasmin, Bigalke, Hans, Perry, Kay, Shoemaker, Charles B., Rummel, Andreas, Jin, Rongsheng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545708/
https://ncbi.nlm.nih.gov/pubmed/22363010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1214270
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