Embryonic exposure to propylthiouracil disrupts left-right patterning in Xenopus embryos

Antithyroid medications are the preferred therapy for the treatment of Graves' disease during pregnancy. Propylthiouracil (PTU) is favored over methimazole (MMI) due to potential teratogenic concerns with MMI. This study was to determine the teratogenic potential of MMI and PTU using a validate...

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Detalhes bibliográficos
Main Authors: van Veenendaal, Nicole R., Ulmer, Bärbel, Boskovski, Marko T., Fang, Xiefan, Khokha, Mustafa K., Wendler, Christopher C., Blum, Martin, Rivkees, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545537/
https://ncbi.nlm.nih.gov/pubmed/23150524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-218073
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