Embryonic exposure to propylthiouracil disrupts left-right patterning in Xenopus embryos

Antithyroid medications are the preferred therapy for the treatment of Graves' disease during pregnancy. Propylthiouracil (PTU) is favored over methimazole (MMI) due to potential teratogenic concerns with MMI. This study was to determine the teratogenic potential of MMI and PTU using a validate...

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Autori principali: van Veenendaal, Nicole R., Ulmer, Bärbel, Boskovski, Marko T., Fang, Xiefan, Khokha, Mustafa K., Wendler, Christopher C., Blum, Martin, Rivkees, Scott A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2013
Soggetti:
Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545537/
https://ncbi.nlm.nih.gov/pubmed/23150524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-218073
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