Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left-Right Organizer in Xenopus

Congenital heart disease (CHD) is the most common birth defect, yet its genetic causes continue to be obscure. Fibroblast growth factor receptor 4 (FGFR4) recently emerged in a large patient exome sequencing study as a candidate disease gene for CHD and specifically heterotaxy. In heterotaxy, patter...

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Bibliografiska uppgifter
I publikationen:Front Physiol
Huvudupphovsmän: Sempou, Emily, Lakhani, Osaamah Ali, Amalraj, Sarah, Khokha, Mustafa K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2018
Ämnen:
Physiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288790/
https://ncbi.nlm.nih.gov/pubmed/30564136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01705
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