The transcriptional landscape of hematopoietic stem cell ontogeny

Transcriptome analysis of adult hematopoietic stem cells (HSC) and their progeny has revealed mechanisms of blood differentiation and leukemogenesis, but a similar analysis of HSC development is lacking. Here, we acquired the transcriptomes of developing HSC purified from >2500 murine embryos and...

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Autors principals: McKinney-Freeman, Shannon, Cahan, Patrick, Li, Hu, Lacadie, Scott A., Huang, Hsuan-Ting, Curran, Matthew, Loewer, Sabine, Naveiras, Olaia, Kathrein, Katie L., Konantz, Martina, Langdon, Erin M., Lengerke, Claudia, Zon, Leonard I., Collins, James J., Daley, George Q.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545475/
https://ncbi.nlm.nih.gov/pubmed/23122293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.07.018
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