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α-Amination of keto-nitrones via Multihetero-Cope rearrangement employing an imidoyl chloride reagent

α-Aminations of ketone-derived nitrones have been developed via [3,3]-rearrangement of the intermediates generated upon condensation with imidoyl chlorides. Careful reagent selection provides synthetically attractive amino protecting groups. The enediamide or α′-carbamoyl enamide products can be hyd...

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Detalhes bibliográficos
Main Authors: Malinowski, Justin T., Malow, Ericka J., Johnson, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545407/
https://ncbi.nlm.nih.gov/pubmed/22733086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc33401a
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