(18)F-click labeling of a bombesin antagonist with an alkyne-(18)F-ArBF(3) (-): in vivo PET imaging of tumors expressing the GRP-receptor

A clickable alkyne-modified arylborimidine is rapidly converted in 15 minutes to a highly polar (18)F-aryltrifluoroborate anion ((18)F-ArBF(3) (-)) at high specific activity. Following labeling, the alkyne-(18)F-ArBF(3) (-) was conjugated to the peptide bombesin (BBN) within 25 minutes in a second s...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Li, Ying, Liu, Zhibo, Harwig, Curtis W, Pourghiasian, Maral, Lau, Joseph, Lin, Kuo-Shyan, Schaffer, Paul, Benard, Francois, Perrin, David M
Formato: Artigo
Lenguaje:Inglês
Publicado: e-Century Publishing Corporation 2013
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545365/
https://ncbi.nlm.nih.gov/pubmed/23342301
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares