Molecular Basis of Immortalization of Human Mesenchymal Stem Cells by Combination of p53 Knockdown and Human Telomerase Reverse Transcriptase Overexpression

Mesenchymal stem cells (MSCs) represent one of the most promising stem cells for a number of degenerative conditions due to their multipotency, immunoprivileged properties, and easy expansion in vitro. However, the limited life span of primary MSCs during in vitro expansion greatly hampers their use...

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Autors principals: Liu, Tong Ming, Ng, Wei Ming, Tan, Hwee San, Vinitha, Denslin, Yang, Zheng, Fan, Jia Bing, Zou, Yu, Hui, James H., Lee, Eng Hin, Lim, Bing
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2013
Matèries:
Original Research Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545350/
https://ncbi.nlm.nih.gov/pubmed/22765508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0222
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