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Molecular Basis of Immortalization of Human Mesenchymal Stem Cells by Combination of p53 Knockdown and Human Telomerase Reverse Transcriptase Overexpression

Mesenchymal stem cells (MSCs) represent one of the most promising stem cells for a number of degenerative conditions due to their multipotency, immunoprivileged properties, and easy expansion in vitro. However, the limited life span of primary MSCs during in vitro expansion greatly hampers their use...

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Detalhes bibliográficos
Main Authors: Liu, Tong Ming, Ng, Wei Ming, Tan, Hwee San, Vinitha, Denslin, Yang, Zheng, Fan, Jia Bing, Zou, Yu, Hui, James H., Lee, Eng Hin, Lim, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545350/
https://ncbi.nlm.nih.gov/pubmed/22765508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2012.0222
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