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MEK1 inactivates Myt1 to regulate Golgi membrane fragmentation and mitotic entry in mammalian cells
The pericentriolar stacks of Golgi cisternae are separated from each other in G2 and fragmented extensively during mitosis. MEK1 is required for Golgi fragmentation in G2 and for the entry of cells into mitosis. We now report that Myt1 mediates MEK1’s effects on the Golgi complex. Knockdown of Myt1...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
European Molecular Biology Organization
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545310/ https://ncbi.nlm.nih.gov/pubmed/23241949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.329 |
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