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The alarmin Mrp8/14 as regulator of the adaptive immune response during allergic contact dermatitis
Mrp8 and Mrp14 are endogenous alarmins amplifying inflammation via Toll-like receptor-4 (TLR-4) activation. Due to their pro-inflammatory properties, alarmins are supposed to enhance adaptive immunity via activation of dendritic cells (DCs). In contrast, analysing a model of allergic contact dermati...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
European Molecular Biology Organization
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545303/ https://ncbi.nlm.nih.gov/pubmed/23188082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.309 |
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