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The alarmin Mrp8/14 as regulator of the adaptive immune response during allergic contact dermatitis

Mrp8 and Mrp14 are endogenous alarmins amplifying inflammation via Toll-like receptor-4 (TLR-4) activation. Due to their pro-inflammatory properties, alarmins are supposed to enhance adaptive immunity via activation of dendritic cells (DCs). In contrast, analysing a model of allergic contact dermati...

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Autors principals: Petersen, Beatrix, Wolf, Marc, Austermann, Judith, van Lent, Peter, Foell, Dirk, Ahlmann, Martina, Kupas, Verena, Loser, Karin, Sorg, Clemens, Roth, Johannes, Vogl, Thomas
Format: Artigo
Idioma:Inglês
Publicat: European Molecular Biology Organization 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545303/
https://ncbi.nlm.nih.gov/pubmed/23188082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.309
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