APLF promotes the assembly and activity of non-homologous end joining protein complexes

Non-homologous end joining (NHEJ) is critical for the maintenance of genetic integrity and DNA double-strand break (DSB) repair. NHEJ is regulated by a series of interactions between core components of the pathway, including Ku heterodimer, XLF/Cernunnos, and XRCC4/DNA Ligase 4 (Lig4). However, the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Grundy, Gabrielle J, Rulten, Stuart L, Zeng, Zhihong, Arribas-Bosacoma, Raquel, Iles, Natasha, Manley, Katie, Oliver, Antony, Caldecott, Keith W
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545299/
https://ncbi.nlm.nih.gov/pubmed/23178593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.304
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados