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APLF (C2orf13) Is a Novel Human Protein Involved in the Cellular Response to Chromosomal DNA Strand Breaks

Aprataxin and polynucleotide kinase (PNK) are DNA end processing factors that are recruited into the DNA single- and double-strand break repair machinery through phosphorylation-specific interactions with XRCC1 and XRCC4, respectively. These interactions are mediated through a divergent class of for...

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Detalhes bibliográficos
Main Authors: Iles, Natasha, Rulten, Stuart, El-Khamisy, Sherif F., Caldecott, Keith W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900005/
https://ncbi.nlm.nih.gov/pubmed/17353262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02269-06
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