Regulation of the Human Hydroxysteroid Sulfotransferase (SULT2A1) by RORα and RORγ and Its Potential Relevance to Human Liver Diseases

The retinoid-related orphan receptors (RORs) were postulated to have functions in tissue development and circadian rhythm. In this study, we revealed a novel function of RORα (NR1F1) and RORγ (NR1F3) in regulating the human hydroxysteroid sulfotransferase (SULT2A1), a phase II conjugating enzyme kno...

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Autori principali: Ou, Zhimin, Shi, Xiongjie, Gilroy, Richard K., Kirisci, Levent, Romkes, Marjorie, Lynch, Caitlin, Wang, Hongbing, Xu, Meishu, Jiang, Mengxi, Ren, Songrong, Gramignoli, Roberto, Strom, Stephen C., Huang, Min, Xie, Wen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2013
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545217/
https://ncbi.nlm.nih.gov/pubmed/23211525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2012-1145
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