Knockouts reveal overlapping functions of M(2) and M(4) muscarinic receptors and evidence for a local glutamatergic circuit within the laterodorsal tegmental nucleus

Cholinergic neurons in the laterodorsal tegmental (LDT) and peduncolopontine tegmental (PPT) nuclei regulate reward, arousal, and sensory gating via major projections to midbrain dopamine regions, the thalamus, and pontine targets. Muscarinic acetylcholine receptors (mAChRs) on LDT neurons produce a...

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Detalhes bibliográficos
Main Authors: Kohlmeier, Kristi A., Ishibashi, Masaru, Wess, Jürgen, Bickford, Martha E., Leonard, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545116/
https://ncbi.nlm.nih.gov/pubmed/22956788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01120.2011
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