A soluble form of Epstein-Barr virus gH/gL inhibits EBV-induced membrane fusion and does not function in fusion

We investigated whether soluble EBV gH/gL (sgH/gL) functions in fusion and made a series of truncations of gH/gL domains based on the gH/gL crystal structure. We found sgH/gL failed to mediate cell-cell fusion both when co-expressed with the other entry glycoproteins and when added exogenously to fu...

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Detaylı Bibliyografya
Asıl Yazarlar: Rowe, Cynthia L., Connolly, Sarah A., Chen, Jia, Jardetzky, Theodore S., Longnecker, Richard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545092/
https://ncbi.nlm.nih.gov/pubmed/23200314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.10.039
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