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Non-specific recognition is achieved in Pot1pC through the use of multiple binding modes
Pot1 is the protein responsible for binding to and protecting the 3’ single-stranded DNA (ssDNA) overhang at most eukaryotic telomeres. Here we present the crystal structure of one of the two OB-folds (Pot1pC) that make up the ssDNA-binding domain in S. pombe Pot1. Comparison with the homologous hum...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545015/ https://ncbi.nlm.nih.gov/pubmed/23201273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.10.015 |
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