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Non-specific recognition is achieved in Pot1pC through the use of multiple binding modes

Pot1 is the protein responsible for binding to and protecting the 3’ single-stranded DNA (ssDNA) overhang at most eukaryotic telomeres. Here we present the crystal structure of one of the two OB-folds (Pot1pC) that make up the ssDNA-binding domain in S. pombe Pot1. Comparison with the homologous hum...

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書誌詳細
主要な著者: Dickey, Thayne H., McKercher, Marissa A., Wuttke, Deborah S.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545015/
https://ncbi.nlm.nih.gov/pubmed/23201273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.10.015
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