The Genotypic False Positive Rate Determined by V3 Population Sequencing Can Predict the Burden of HIV-1 CXCR4-using Species Detected by Pyrosequencing

OBJECTIVE: The false-positive rate (FPR) is a percentage-score provided by Geno2Pheno-algorithm indicating the likelihood that a V3-sequence is falsely predicted as CXCR4-using. We evaluated the correlation between FPR obtained by V3 population-sequencing and the burden of CXCR4-using variants detec...

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Detalhes bibliográficos
Main Authors: Svicher, Valentina, Cento, Valeria, Rozera, Gabriella, Abbate, Isabella, Santoro, Maria Mercedes, Armenia, Daniele, Fabeni, Lavinia, Bruselles, Alessandro, Latini, Alessandra, Palamara, Guido, Micheli, Valeria, Rizzardini, Giuliano, Gori, Caterina, Forbici, Federica, Ippolito, Giuseppe, Andreoni, Massimo, Antinori, Andrea, Ceccherini-Silberstein, Francesca, Capobianchi, Maria Rosaria, Perno, Carlo Federico
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544916/
https://ncbi.nlm.nih.gov/pubmed/23341955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053603
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