Kar3Vik1 Uses a Minus-End Directed Powerstroke for Movement along Microtubules

We have used cryo-electron microscopy (cryo-EM) and helical averaging to examine the 3-D structure of the heterodimeric kinesin-14 Kar3Vik1 complexed to microtubules at a resolution of 2.5 nm. 3-D maps were obtained at key points in Kar3Vik1’s nucleotide hydrolysis cycle to gain insight into the mec...

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Bibliografiske detaljer
Main Authors: Cope, Julia, Rank, Katherine C., Gilbert, Susan P., Rayment, Ivan, Hoenger, Andreas
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544905/
https://ncbi.nlm.nih.gov/pubmed/23342004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053792
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