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Kar3Vik1 Uses a Minus-End Directed Powerstroke for Movement along Microtubules
We have used cryo-electron microscopy (cryo-EM) and helical averaging to examine the 3-D structure of the heterodimeric kinesin-14 Kar3Vik1 complexed to microtubules at a resolution of 2.5 nm. 3-D maps were obtained at key points in Kar3Vik1’s nucleotide hydrolysis cycle to gain insight into the mec...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3544905/ https://ncbi.nlm.nih.gov/pubmed/23342004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053792 |
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