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Establishment of HRAS(G12V) Transgenic Medaka as a Stable Tumor Model for In Vivo Screening of Anticancer Drugs

Most targeted anticancer drugs have been identified by screening at the molecular or cellular level in vitro. However, many compounds selected by such costly and time-consuming screening do not prove effective against tumors in vivo. The development of anticancer drugs would thus be facilitated by t...

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Bibliografische gegevens
Hoofdauteurs: Matsuzaki, Yuriko, Hosokai, Haru, Mizuguchi, Yukiyo, Fukamachi, Shoji, Shimizu, Atsushi, Saya, Hideyuki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544794/
https://ncbi.nlm.nih.gov/pubmed/23342156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054424
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