Enhancement of Auranofin-Induced Apoptosis in MCF-7 Human Breast Cells by Selenocystine, a Synergistic Inhibitor of Thioredoxin Reductase

Thioredoxin system plays an important role in regulation of intracellular redox balance and various signaling pathways. Thioredoxin reductase (TrxR) is overexpressed in many cancer cells and has been identified as a potential target of anticancer drugs. Auranofin (AF) is potent TrxR inhibitor with n...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Liu, Chaoran, Liu, Zhong, Li, Meng, Li, Xiaoling, Wong, Yum-Shing, Ngai, Sai-Ming, Zheng, Wenjie, Zhang, Yibo, Chen, Tianfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544722/
https://ncbi.nlm.nih.gov/pubmed/23342042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053945
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados