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Contributions of PHOX2B in the Pathogenesis of Hirschsprung Disease

Hirschsprung disease (HSCR) is a congenital malformation of the hindgut resulting from a disruption of neural crest cell migration during embryonic development. It has a complex genetic aetiology with several genes involved in its pathogenesis. PHOX2B plays a key function in the development of neura...

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Autors principals: Fernández, Raquel María, Mathieu, Yves, Luzón-Toro, Berta, Núñez-Torres, Rocío, González-Meneses, Antonio, Antiñolo, Guillermo, Amiel, Jeanne, Borrego, Salud
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544660/
https://ncbi.nlm.nih.gov/pubmed/23342068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054043
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