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Contributions of PHOX2B in the Pathogenesis of Hirschsprung Disease
Hirschsprung disease (HSCR) is a congenital malformation of the hindgut resulting from a disruption of neural crest cell migration during embryonic development. It has a complex genetic aetiology with several genes involved in its pathogenesis. PHOX2B plays a key function in the development of neura...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3544660/ https://ncbi.nlm.nih.gov/pubmed/23342068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054043 |
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