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Signal Amplification by Glyco-qPCR for Ultrasensitive Detection of Carbohydrates: Applications in Glycobiology

Tiny amounts of carbohydrates (ca. 1 zmol) can be detected quantitatively by a real-time method based on the conjugation of carbohydrates with DNA markers (see picture). The proposed method (glyco-qPCR) provides uniform, ultrasensitive detection of carbohydrates, which can be applied to glycobiology...

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Autors principals: Kwon, Seok Joon, Lee, Kyung Bok, Solakyildirim, Kemal, Masuko, Sayaka, Ly, Mellisa, Zhang, Fuming, Li, Lingyun, Dordick, Jonathan S., Linhardt, Robert J.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544480/
https://ncbi.nlm.nih.gov/pubmed/23073897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201205112
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