Controlled Photochemical Depolymerization of K5 Heparosan, a Bioengineered Heparin Precursor

Heparosan is a polysaccharide, which serves as the critical precursor in heparin biosynthesis and chemoenzymatic synthesis of bioengineered heparin. Because the molecular weight of microbial heparosan is considerably larger than heparin, the controlled depolymerization of microbial heparosan is nece...

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Main Authors: Higashi, Kyohei, Ly, Mellisa, Wang, Zhenyu, Masuko, Sayaka, Bhaskar, Ujjwal, Sterner, Eric, Zhang, Fuming, Toida, Toshihiko, Dordick, Jonathan S., Linhardt, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153860/
https://ncbi.nlm.nih.gov/pubmed/21841848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carbpol.2011.06.042
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